In 1995 the freight house, one of the last remaining railroad buildings in town, burned due to arson.
In 1984 the last train arrived in and departed Keene, consisting of Boston & Maine EMD GP9 1714 with flat cars for rail removed from the railyard.
Track conditions on the Ashuelot Branch were so poor at the time that the engine returned light to Brattleboro, and a hi-rail truck was used to remove the flatcars instead.
Keene became a manufacturing center for wooden-ware, pails, chairs, sashes, shutters, doors, pottery, glass, soap, woolen textiles, shoes, saddles, mowing machines, carriages and sleighs. Keene was incorporated as a city in 1874, and by 1880 had a population of 6,784.
After the railroad arrived in 1848, numerous other industries were established.
Route 10 leads north to Newport and southwest to Northfield, Massachusetts.
Route 12 leads northwest to Walpole and Charlestown and southeast to Winchendon, Massachusetts.During the summer, Keene can get hit by thunderstorms from the west, but the Green Mountains to the west often break up some of the storms, so that Keene doesn't usually experience a thunderstorm at full strength.The last time a tornado hit Cheshire County was in 1997. The most recent such winter was 2002–2003, when Keene received 112.5 inches (2,860 mm) of snow.Keene is served by Dillant–Hopkins Airport, located just south of the city in Swanzey.Keene is located in a humid continental climate zone. The average high temperature in July is 82 °F (28 °C), and the record high for Keene is 102 °F (39 °C). S., periods of high humidity can raise heat indices to near 110 °F (43 °C). Lamoureux Settled after 1736, it was intended to be a fort town protecting the Province of Massachusetts Bay during the French and Indian Wars.