Because some can cause serious side effects or interact with other medications you are taking, be sure to let your doctor know all the medications you take.
Claritin-D 24 hour (10mg loratadine 240mg psuedophedrine) Dosing (Adult): one tablet po qd. Approval: 2013 Mechanism of Action: Carbinoxamine is an H1 receptor antagonist (antihistamine) that exhibits anticholinergic (drying) and sedative properties.
Claritin-D 24 Hour Extended Release Tablets should generally be avoided in patients with hepatic insufficiency. Antihistamines compete with histamine for receptor sites on effector cells.
You may have taken antihistamines in the past and found it hard to concentrate or stay awake.
For many people, sedating antihistamines, also called old, classic, or first-generation antihistamines, cause sleepiness, grogginess, and slow reaction time.
Fexofenadine hydrochloride inhibited antigen-induced bronchospasm in sensitized guinea pigs and histamine release from peritoneal mast cells in rats.
The clinical significance of these findings is unknown.
Receptor binding data indicate that at a concentration of 2–3 ng/m L (7 nanomolar), desloratadine shows significant interaction with the human histamine H1-receptor.
Desloratadine inhibited histamine release from human mast cells in vitro.
They may interfere with coordination and cloud your concentration.
Many sedating antihistamines do not require a doctor's prescription.
A dose of 60 mg once daily is recommended as the starting dose in patients with decreased renal function Mechanism of Action Fexofenadine hydrochloride, the major active metabolite of terfenadine, is an antihistamine with selective peripheral H1-receptor antagonist activity.